Header Ads

U.S. approves breakthrough drug for treatment of Alzheimer’s disease

 The United States Food and Drug Administration has approved a drug for the treatment of Alzheimer’s disease, a landmark decision that stands to change treatment regime for the memory condition.  Alzheimer’s disease is the sixth-leading cause of death in the United States.

Reuters reports that U.S. regulators on Monday approved Aducanumab pushed forward by Biogen Inc. as the first treatment to address Alzheimer’s disease, despite controversy over mixed clinical trial results for the drug. The drug will be marketed under the name Aduhelm and is expected to generate billions of dollars in revenue for the company.

“We are well-aware of the attention surrounding this approval,” Dr. Patrizia Cavazzoni, director of the FDA’s Center for Drug Evaluation and Research, said in a press release. “We understand that Aduhelm has garnered the attention of the press, the Alzheimer’s patient community, our elected officials, and other interested stakeholders.

Aducanumab is designed to remove sticky deposits of a protein called amyloid beta in the brain, which is believed to be a cause of Alzheimer’s disease. Most of the drugs designed for Alzheimer’s have attempted to clear these plaques.

The now-approved drug, Aducanumab, appears to do this in some patients, but only at an early stage in the disease. 

Approval of this medication means that early testing would be encouraged to establish that a patient may have the disease. Patients with early memory problems will need scans of the brain to establish whether they have amyloid plaques. 

With Biogen estimating that around 1.5 million Americans would be eligible for treatment with Aducanumab, which is given by monthly infusion, concerns are raised as to the running costs and how it will affect the healthcare system, as it requires not only equipment but also trained staff.

The healthcare community is divided over Biogen’s drug, with some neurologists eager to have an effective option for patients with the lethal disease, which includes deteriorating memory loss and the ability to care for oneself, and other doctors noting that the clinical trial results were inconsistent and more proof would be needed.

At the trial stages, some patients developed potentially dangerous brain swelling when Aducanumab was used on patients who tested positive for a component of amyloid brain plaques at the early stage.  Two trials were stopped in March 2019 when an analysis concluded the studies would not reach their goal of slowing cognitive and functional impairment in participants.  

The manufacturer, Biogen, said the drugs were unlikely to improve people’s memory and thinking but the company later announced that a reanalysis of more patient data from one of the trials involving people who had taken the drugs for longer showed that a high dose could slow the decline of memory and thinking skills and the ability to carry out activities in daily life.

Hilary Evans, the chief executive of Alzheimer’s Research UK, told the Guardian; “People with dementia and their families have been waiting far too long for life-changing new treatments but they need treatments that are safe and effective. 

“Biogen’s decision to file for a licence for aducanumab came as a surprise to some doctors and researchers who had voiced concerns that the data is not yet strong enough to suggest aducanumab brings the benefits that people with Alzheimer’s and their families would rightly expect. It’s important we see a robust and evidence-based decision from regulators on whether any new medicine is safe and effective.”

Over six million Americans are living with the disease, according to estimates by the Alzheimer’s Association. The group projects that by 2050, the number will rise to about 13 million Americans. 

No comments

Thank you for reaching out to us. We are happy to receive your opinion and request. If you are need advert or sponsored post, We’re excited you’re considering advertising or sponsoring a post on our blog. Your support is what keeps us going. With the current trend, it’s very obvious content marketing is the way to go. Banner advertising and trying to get customers through Google Adwords may get you customers but it has been proven beyond doubt that Content Marketing has more lasting benefits.
We offer majorly two types of advertising:
1. Sponsored Posts: If you are really interested in publishing a sponsored post or a press release, video content, advertorial or any other kind of sponsored post, then you are at the right place.
Generally, a sponsored post can be any of the following:
Press release
Video content
This kind of post is usually written to promote you or your business. However, we do prefer posts that naturally flow with the site’s general content. This means we can also promote artists, songs, cosmetic products and things that you love of all products or services.
Every sponsored article will remain live on the site as long as this website exists. The duration is indefinite! Again, we will share your post on our social media channels and our email subscribers too will get to read your article. You’re exposing your article to our: Twitter followers, Facebook fans and other social networks.

We will also try as much as possible to optimize your post for search engines as well.

Submission of Materials : Sponsored post should be well written in English language and all materials must be delivered via electronic medium. All sponsored posts must be delivered via electronic version, either on disk or e-mail on Microsoft Word unless otherwise noted.
The price largely depends on if you’re writing the content or we’re to do that. But if your are writing the content, it is $60 per article.

2. Banner Advertising: We also offer banner advertising in various sizes and of course, our prices are flexible. you may choose to for the weekly rate or simply buy your desired number of impressions.

Technical Details And Pricing
Banner Size 300 X 250 pixels : Appears on the home page and below all pages on the site.
Banner Size 728 X 90 pixels: Appears on the top right Corner of the homepage and all pages on the site.
Large rectangle Banner Size (336x280) : Appears on the home page and below all pages on the site.
Small square (200x200) : Appears on the right side of the home page and all pages on the site.
Half page (300x600) : Appears on the right side of the home page and all pages on the site.
Portrait (300x1050) : Appears on the right side of the home page and all pages on the site.
Billboard (970x250) : Appears on the home page.

Submission of Materials : Banner ads can be in jpeg, jpg and gif format. All materials must be deliverd via electronic medium. All ads must be delivered via electronic version, either on disk or e-mail in the ordered pixel dimensions unless otherwise noted.
For advertising offers, send an email with your name,company, website, country and advert or sponsored post you want to appear on our website to omodjk(at)gmail(dot)com

Normally, we should respond within 48 hours.